Michigan health officials reported on Monday, August 4th, 2026, what appear to be the first deaths connected to the ongoing cyclospora outbreak in the United States. Both individuals had significant underlying health conditions and became ill before the voluntary recall of iceberg lettuce.

State officials noted that death resulting from cyclosporiasis is uncommon in the U.S. The outbreak has drawn attention due to symptoms including notable diarrhea, but it can also cause a range of gastrointestinal issues. Some patients may experience no symptoms, which federal health officials say could lead to underreporting of cases.

Dr. Miguel Cabada, Associate Professor in the Division of Infectious Diseases at the University of Texas Medical Branch, told Nexstar via email that cyclospora infections vary widely, from asymptomatic to prolonged illness. Among symptomatic patients, fatigue, weight loss, and watery diarrhea are common but generally mild.

A California woman affected by the infection told KTLA she lost nearly 10 pounds within a week before seeking medical care. Treatment options include antibiotics, antidiarrheal medications, and hydration, according to the Cleveland Clinic.

Sources